Is it ever too early to consider new drug pricing strategy?

Is it ever too early to consider new drug pricing strategy?
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Planning for Pharma Partnering

It's never too early to start For biotechs developing an asset for a pharma partnership, it’s crucial to consider the key deal-success ingredients, in the eyes of a future pharma partner, well in...
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Experts and Witnesses: Two Sides of the Same Coin

It surprises, and occasionally alarms, even experienced experts familiar with undertaking due diligence on behalf of investors or corporations to realize their knowledge, skills and attributes make...
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The Rise and Rise of Antibody-Drug Conjugates

The path of the "magic bullet" Around the turn of the last century, Paul Ehrlich postulated that tailored and targeted drug delivery might be a means of treating disease1. Some eighty years later,...
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Do Price and Value Assumptions Belong in a Target Product Profile?

We often get pushback from clients about the merit of including launch price assumptions and value proposition statements in the target product profile (TPP) for early-stage development programs....
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Maybe they should start calling it Decelerated Approval?

The FDA is proposing that a single trial could support both accelerated and full approval of oncology therapeutics. At first glance this seems to be a promising development. Though, as one reads more...
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Beyond rNPV Valuations

Many valuation purists believe that a risk-adjusted net present value (rNPV) is the be-all and end-all of the value of a pharmaceutical asset. After all, it captures all the best insights into future...
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Cancer Vaccines: Ready for Prime Time or Another False Dawn?

Cancer Vaccines: Ready for Prime Time or Another False Dawn? Moderna and BioNTech recently reported positive early clinical data for mRNA cancer vaccines in combination with PD-1/L1 inhibitors, so...
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Drug Repurposing: Realities and Roadblocks

Drug Repurposing Market: Realities and Roadblocks We receive a steady stream of enquiries about opportunities in drug repurposing, often from people who see a short, low risk pathway to large...
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The race is on: after almost six decades, RSV vaccines near the finish line

The COVID-19 pandemic established that, when push comes to shove, successful vaccine development and deployment can be conducted at breakneck speed, even when largely untried and untested...
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For pharma & biotech, what's the value of a valuation?

When a client approaches us about conducting a valuation for them, our first question is always: why? If, for example, the reason is to help support them in a partnering negotiation, we proceed...
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Targeted protein degradation: a new pharmacology paradigm?

Traditional drug development focuses on targeting proteins with a defined binding pocket or active site to regulate protein activity. These strategies have exploited only around 400 of the 4000...
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